Complex CDK4_6*:CIP1_KIP1*:CyclinD* map
Complex composition:

  1. CDK4_6* map
  2. CyclinD* map
  3. CIP1_KIP1* map

(CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@Nucleus

Identifiers
NAME:CDK4_6*:CIP1_KIP1*:CyclinD*

Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
 Cell Cycle DNA Repair  map  / G1_S_CHECKPOINT  map
 Cell Cycle DNA Repair  map  / G1_CC_PHASE  map

References
p53-dependentG1/S checkpoint
ce_re115( Cell Cycle DNA Repair  map ):
PMID:16581787,
For inhibition of S-checkpoint by ATM:
PMID:15175241
Inhibition of Sphase by MRE complex:
PMID:17713585
By CycE*/CDK2: G1/S transition
By CycD*/CDK2/CIp/KIP: checkpoint G1/S

Modifications:
Participates in complexes:
In compartment: Nucleus
  1. (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. (CDK4_6*|​T172_pho:​CyclinD*)|​active@Nucleus map + CIP1_KIP1*@Nucleus map → map (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@Nucleus map
  2. (CDK4_6*:​CIP1_KIP1*:​CyclinD*)|​active@Nucleus map → map CIP1_KIP1*@Nucleus map + (CDK4_6*|​T172_pho:​CyclinD*)|​active@Nucleus map
As Catalyser:
  1. G1 phase@Nucleus map → map S phase@Nucleus map
  2. E2F1:​RB1@Nucleus map → map E2F1:​RB1|​pho@Nucleus map
  3. E2F4_5*:​p107*@Nucleus map → map E2F4_5*:​p107*|​pho@Nucleus map