Complex GRB2:RAF1:RAS*:RTK*:SOS*
Complex composition:
- RAF1
- GRB2
- SOS*
- RTK*
- RAS*
GRB2:RAF1|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane
Identifiers
NAME:GRB2:RAF1:RAS*:RTK*:SOS*
References
su_mpk1_mpk1_re102( Survival
):
When Ras assumes an active conformation through binding of GTP a subpopulation of the Raf-1 (C-Raf) protein molecules in cells translocates from the cytosol to the plasma membrane via interaction with P21ras (not modelled).
PMID:8929532
su_mpk1_mpk1_re103( Survival
):
BCL2 protein can target Raf-1 (C-Raf) to mitochondria.
Modifications:
Participates in complexes:
In compartment: Plasma Membrane
- GRB2:RAF1|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane
Participates in reactions:
As Reactant or Product:- RAF1@Cytoplasm
+ GRB2:RAS*|pho:RTK*:SOS*@Plasma Membrane
→
GRB2:RAF1|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane
- GRB2:RAF1|pho:RAS*|pho:RTK*:SOS*@Plasma Membrane
→
GRB2:RAS*|pho:RTK*:SOS*@Plasma Membrane
+ RAF1|pho@Mitochondria
As Catalyser: