Reaction dissociation re143 map

L-arginine@Cytosol map → Urea@Cytosol map + L-ornitine@Cytosol map

Reaction regulators:
Catalysis
  1. p38*|​pho|​active@Cytosol map
  2. ARG1@Cytosol map
  3. ARG2@Cytosol map
  4. STAT6|​pho|​active@Cytosol map
  5. PKA*@Cytosol map





Identifiers

Maps_Modules

References
PMID:10925299
IL13 activates Arginase activity downstream of cAMP/PKA
PMID:14568929, PMID:10925299
IL13 induces arginase activity which results in L-arginin deficiency. L-arginin deficiency impairs iNOS protein synthesis and stability.
p38 MAPK participates in arginase activation??downstream of IL13