Protein CHUK map

Identifiers
HUGO:CHUK

Maps_Modules
MODULE:MACROPHAGE
MODULE:MDSC
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:17485448
TNIP3 (ABIN3???) ???inhibits IKK complex trough direct binding to IKBKG.
It results in inhibition of??? ???FNKBIA phosphorylation and
proteasomal degradation and prevents activation
of downstream??? ???NFkB??? ???signaling??? ???downstream of IL10.

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. CHUK:​IKBKG:​IKK_beta_*@Cytosol map
  2. CHUK:​IKBKG|​ubi:​IKK_beta_*|​pho@Cytosol map
  3. CHUK:​IKBKG:​IKK_beta_*:​TNIP3@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. CHUK:​IKBKG:​IKK_beta_*@Cytosol map → map CHUK:​IKBKG|​ubi:​IKK_beta_*|​pho@Cytosol map
  2. TNIP3@Cytosol map + CHUK:​IKBKG:​IKK_beta_*@Cytosol map → map CHUK:​IKBKG:​IKK_beta_*:​TNIP3@Cytosol map
As Catalyser:
  1. NFKB1_p50*:​NFKBIA:​RELA@Cytosol map → map NFKB1_p50*:​NFKBIA|​pho:​RELA|​pho@Cytosol map