Identifiers
NAME:CHUK:IKBKG:IKK_beta_*:TNIP3
Maps_Modules
MODULE:MACROPHAGE
References
complex
PMID:17485448
TNIP3 (ABIN3???) ???inhibits IKK complex trough direct binding to IKBKG.
It results in inhibition of??? ???FNKBIA phosphorylation and
proteasomal degradation and prevents activation
of downstream??? ???NFkB??? ???signaling??? ???downstream of IL10.
PMID:17485448, PMID:10542212
Inhibition of NfkB signaling downstream of ABIN3 inhibits expression of IL8, IL6, TNFa, IL12p40