Protein TNIP3 map

Identifiers
HUGO:TNIP3

Maps_Modules
MODULE:MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:17485448
TNIP3 (ABIN3???) ???inhibits IKK complex trough direct binding to IKBKG.
It results in inhibition of??? ???FNKBIA phosphorylation and
proteasomal degradation and prevents activation
of downstream??? ???NFkB??? ???signaling??? ???downstream of IL10.
PMID:17485448, PMID:10542212
Inhibition of NfkB signaling downstream of ABIN3 inhibits expression of IL8, IL6, TNFa, IL12p40 ()

TNIP3@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. TNIP3@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. CHUK:​IKBKG:​IKK_beta_*:​TNIP3@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. rTNIP3@Cytosol map → map TNIP3@Cytosol map
  2. TNIP3@Cytosol map + CHUK:​IKBKG:​IKK_beta_*@Cytosol map → map CHUK:​IKBKG:​IKK_beta_*:​TNIP3@Cytosol map
As Catalyser:
  1. NFKB1_p50*:​NFKBIA:​RELA@Cytosol map → map NFKB1_p50*:​NFKBIA|​pho:​RELA|​pho@Cytosol map