Protein GSK3_beta_* map

Identifiers
HUGO:GSK3B

Maps_Modules
MODULE:MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:16713974
GSK3B inhitits activation (DNA binding) of AP-1 factors.
GSK3B is activated downstrean of IFNG via PI3K pathway.
PMID:16007092
GSK3B inhibits CREB1 interaction with CBP and inhibits CREB1 dependent IL10 expression.
CREB1/CBP complex formation prevents binding CBP to RELA (p65) and inhibits downstream NF-kB signaling.

GSK3_beta_*|​pho@Cytosol

Identifiers

Maps_Modules

References

GSK3_beta_*@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. GSK3_beta_*@Cytosol map
  2. GSK3_beta_*|​pho@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. GSK3_beta_*@Cytosol map → map GSK3_beta_*|​pho@Cytosol map
    2. GSK3_beta_*@Cytosol map → map GSK3*@Cytosol map
    As Catalyser:
    1. CREB1@Cytosol map → map CREB1|​pho|​active@Cytosol map
    2. AP1*@Cytosol map → map AP1*@Cytosol map
    3. CBP*@Cytosol map + RELA@Cytosol map → map CBP*:​RELA@Cytosol map
    4. CREB1|​pho|​active@Cytosol map + CBP*@Cytosol map → map CBP*:​CREB1|​pho@Cytosol map