Reaction heterodimer_association re430 map

CBP*@Cytosol map + RELA@Cytosol map → CBP*:​RELA@Cytosol map

Reaction regulators:
Catalysis
  1. GSK3_beta_*@Cytosol map
Inhibition
  1. CBP*:​CREB1|​pho@Cytosol map





Identifiers

Maps_Modules

References
PMID:16007092
GSK3B induces RELA (p65) interaction with CBP and activates downstream NF-kB signaling end expression of proinflammatory cytokines.
CREB1/CBP complex formation prevents binding CBP to RELA (p65) and inhibits downstream NF-kB signaling.