Protein TAB2 map

Identifiers
HUGO:TAB2

Maps_Modules
MODULE:MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:14660645, PMID:18264787, PMID:12620219
IRAK-1 interacts with the downstream adaptor TRAF6,
resulting in formation of a complex that also includes TAK1 and TAB2.
IRAK-1 mediates the translocation of TRAF6, TAK1 and TAB2 to the cytosol,
where they form a multiprotein complex with other cytosolic proteins,
which are needed for stimulation of TAK1 kinase activity.

TAB2@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. TAB2@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. MAP3K7:​TAB2@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. MAP3K7@Cytosol map + TAB2@Cytosol map → map MAP3K7:​TAB2@Cytosol map
As Catalyser:
  1. CHUK:​IKBKG:​IKK_beta_*@Cytosol map → map CHUK:​IKBKG|​ubi:​IKK_beta_*|​pho@Cytosol map