Phenotype Hypoxia map
Hypoxia@default

Identifiers

Maps_Modules
MODULE:MACROPHAGE

References
PMID:16127144
HIF-1A and HIF-2A are up-regulated by human macrophages exposed to hypoxia??in vitro??and by TAMs in hypoxic/necrotic areas of human tumors
PMID:17164174
Hypoxia (0.5% O2) elicits macrophages to produce higher levels of O2*-, TGF-beta, and VEGF than normoxia.

Modifications:
In compartment: default
  1. Hypoxia@default map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Hypoxia@default map → map lactic acid @default map
    As Catalyser:
    1. HIF2A*@Cytosol map → map HIF2A*@Cytosol map
    2. HIF1A@Cytosol map → map HIF1A@Cytosol map