Complex MAP3K7:TAB* map
Complex composition:

  1. MAP3K7 map
  2. TAB* map

MAP3K7:​TAB*|​pho@T_cell

Identifiers
NAME:MAP3K7:TAB*

References
ad_re400( Adaptive Immune Response  map ):
PMID:14660645, PMID:18264787, PMID:11460167
Activated TAK1 phosphorylates IKK-beta proteins
leading to activation of NF-??B downstream of HMGB1.
PMID:21232017, PMID:21133840, PMID:17301840
PMID:24958845, PMID:24699077
The LUBAC complex ubiquitinates NEMO, a subunit of the IKK complex downstream of TNF and upregulates IkBa degradetion.
PMID:11280761
VEGF signaling blocs TNF-?? induced activation of I??B kinase (IKK complex).This decreased IKK activation correlated with the inhibition of I??B?? phosphorylation and degradation of I??B?? and I??B?? in HPCs, and this inhibition is inhdependent or FLT1 and KDR

Modifications:
Participates in complexes:
In compartment: T_cell
  1. MAP3K7:​TAB*|​pho@T_cell map
Participates in reactions:
As Reactant or Product:
  1. TAB*@T_cell map + MAP3K7@T_cell map → map MAP3K7:​TAB*|​pho@T_cell map
  2. MAP3K7:​TAB*|​pho@T_cell map → map TAB*@T_cell map + MAP3K7@T_cell map
As Catalyser:
  1. MAP2K4@T_cell map → map MAP2K4|​pho@T_cell map
  2. IKBKG:​IKK_alpha_*:​IKK_beta_*@T_cell map → map IKBKG|​ubi:​IKK_alpha_*:​IKK_beta_*|​pho@T_cell map
  3. gIL2RA@T_cell map → map rIL2RA@T_cell map
  4. gFOXP3@T_cell map → map rFOXP3@T_cell map
  5. MAP2K3@T_cell map → map MAP2K3|​pho@T_cell map
  6. MAP2K6@T_cell map → map MAP2K6|​pho@T_cell map