Protein TAB* map

Identifiers
HUGO:TAB1 HUGO:TAB2 HUGO:TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 2
HUGO:TAB2 HGNC:17075 ENTREZ:23118 UNIPROT:Q9NYJ8
TGF-beta activated kinase 1/MAP3K7 binding protein 3
HUGO:TAB3 HGNC:30681 ENTREZ:257397 UNIPROT:Q8N5C8
TGF-beta activated kinase 1/MAP3K7 binding protein 1
MAP3K7IP1 "mitogen-activated protein kinase kinase kinase 7 interacting protein 1"
HUGO:TAB1 HGNC:18157 ENTREZ:10454 UNIPROT:Q15750
MAP3K7IP2 "mitogen-activated protein kinase kinase kinase 7 interacting protein 2"
MAP3K7IP3 "mitogen-activated protein kinase kinase kinase 7 interacting protein 3"

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / TNF_RESPONSE  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / MAPK  map

References
PMID:16200688 PMID:15282297 PMID:24403530
TAK1 is the only MAP3K that requires the adapter proteins TAB123 for its activation.
PMID:20060931

Modifications:
In compartment: T_cell
  1. TAB*@T_cell map
Participates in complexes:
In compartment: T_cell
  1. MAP3K7:​TAB*|​pho@T_cell map
Participates in reactions:
As Reactant or Product:
  1. TAB*@T_cell map + MAP3K7@T_cell map → map MAP3K7:​TAB*|​pho@T_cell map
  2. MAP3K7:​TAB*|​pho@T_cell map → map TAB*@T_cell map + MAP3K7@T_cell map
As Catalyser:
  1. MAP2K4@T_cell map → map MAP2K4|​pho@T_cell map
  2. IKBKG:​IKK_alpha_*:​IKK_beta_*@T_cell map → map IKBKG|​ubi:​IKK_alpha_*:​IKK_beta_*|​pho@T_cell map
  3. gIL2RA@T_cell map → map rIL2RA@T_cell map
  4. gFOXP3@T_cell map → map rFOXP3@T_cell map
  5. MAP2K3@T_cell map → map MAP2K3|​pho@T_cell map
  6. MAP2K6@T_cell map → map MAP2K6|​pho@T_cell map