Reaction state_transition ce_re71 map

EXO1@Nucleus map → EXO1|​S692_pho|​S372_pho|​S567_pho|​S587_pho@Nucleus map

Reaction regulators:
Catalysis
  1. CHEK2|​pho|​active@Nucleus map
  2. ATM|​S1981_pho|​S367_pho|​S1893_pho|​active@Nucleus map
  3. ATR|​pho|​active@Nucleus map
Modulation
  1. TP53BP1@Nucleus map


References
For inactivation of EXO1 by 53BP1-mediated phosphorylation:
PMID:18756267, PMID:15867354
ATM and ATR phosphorylate EXO1 and lead to EXO1 ubiquitination and degradation:
PMID:18048416, PMID:11438669, PMID:20019063