Identifiers
NAME:RAD18:RAD6*
Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
Cell Cycle DNA Repair / TLS
References
ce_re168( Cell Cycle DNA Repair ):
PMID:18157158
Ubiquitination of PCNA by RAD6-RAD18 increases affinity of PCNA to POLH and makes switch from PCNA-POLD to PCNA-POLH and stops translation and initiates TLS pathway
PMID:15280666, PMID:18498753
ce_re236( Cell Cycle DNA Repair ):
Recruitment of all components as POLH and RAD6/RAD18 that ubiguitinate PCNA all together activate TLS:
PMID:16824193