Identifiers
NAME:Caspase3*:DCC:NTN1
References
DCC:Caspase3*:NTN1
PMID:19543238
netrin-1 triggers the multimerization of both DCC and UNC5H2 receptors, and that multimerization of the intracellular domain of DCC and UNC5H2 is the critical step to inhibit the proapoptotic effects of both of these receptors
rc_re1690( Regulated Cell Death ):
Interfering with multimerization of netrin-1 receptors triggers tumor cell death