Complex GJA3_8_GJB1_GJB2*:GJB1 map
Complex composition:

  1. GJB1 map
  2. GJA3_8_GJB1_GJB2* map


GJA3_8_GJB1_GJB2*:​GJB1@Neighbouring Cell

Identifiers
NAME:GJA3_8_GJB1_GJB2*:GJB1

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / GAP_JUNCTIONS  map

References
GJB1 is so-called Connexin 32 or Cx32
PMID:9592087
Cx32 (GJB1) interacts with Cx26(GJB2), Cx46(GJA3), and Cx50(GJA8) but failing to do so with Cx40(GJA5).
PMID:15782139
Cx32 has a strong tumor-suppressive effect on a human metastatic renal cell carcinoma cell line.
Cx32-dependent inactivation of Src decreased the production of VEGF via the suppression of Stat3 activation


Modifications:
Participates in complexes:
In compartment: Neighbouring Cell
  1. GJA3_8_GJB1_GJB2*:​GJB1@Neighbouring Cell map
Participates in reactions:
As Reactant or Product:
  1. GJA3_8_GJB1_GJB2*@Neighbouring Cell map + GJB1@Cytosol map map GJA3_8_GJB1_GJB2*:​GJB1@Neighbouring Cell map
  2. GJA3_8_GJB1_GJB2*:​GJB1@Neighbouring Cell map map Gap junctions@Cytosol map
As Catalyser: