Protein NOTCH1 map

Identifiers
Notch homolog 1
NOTCH intracellular domains NICD
HUGO:NOTCH1, HGNC:7881, ENTREZ:4851, GENECARDS:GC09M139388
notch 1
HUGO:NOTCH1 HGNC:7881 ENTREZ:4851 UNIPROT:P46531

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / LYSOSOME_ENDOSOME  map

References
PMID:20351093
PMID:22363487

NOTCH1@Endosome

References
em_emtc_emtc_re1344:( EMT Senescence  map ) PMID:19567869

Modifications:
In compartment: Endosome
  1. NOTCH1@Endosome map
In compartment: Extracellular space
  1. NOTCH1@Extracellular space map
Participates in complexes:
In compartment: Lysosome
  1. NOTCH1:​NUMB@Lysosome map
  2. JAG1|​ubi:​NOTCH1:​NUMB:​_beta_-Catenin*@Lysosome map
In compartment: Neighbouring Cell
  1. DLL1:​NOTCH1@Neighbouring Cell map
  2. JAG1|​ubi:​NOTCH1@Neighbouring Cell map
Participates in reactions:
As Reactant or Product:
  1. JAG1|​ubi:​NOTCH1@Neighbouring Cell map → map NICD*@Cytosol map
  2. DLL1:​NOTCH1@Neighbouring Cell map → map NICD*@Cytosol map
  3. JAG1|​ubi@Neighbouring Cell map + JAG1|​ubi:​NOTCH1@Neighbouring Cell map → map JAG1|​ubi:​NOTCH1@Neighbouring Cell map
  4. JAG1|​ubi:​NOTCH1@Neighbouring Cell map + _beta_-Catenin*@Cytosol map + NUMB@Cytosol map → map JAG1|​ubi:​NOTCH1:​NUMB:​_beta_-Catenin*@Lysosome map
  5. JAG1|​ubi:​NOTCH1@Neighbouring Cell map → map NOTCH1@Endosome map
  6. NOTCH1@Endosome map → map JAG1|​ubi:​NOTCH1@Neighbouring Cell map
  7. NOTCH1@Endosome map + NUMB@Cytosol map → map NOTCH1:​NUMB@Lysosome map
  8. NOTCH1@Extracellular space map → map N1ICD*@Extracellular space map
As Catalyser: