Complex Ca2+:DAG:RAF1:RAS*:RASGRP1
Complex composition:
- RASGRP1
- RAS*
- RAF1
- DAG
- Ca2+
Ca2+:DAG:RAF1|pho:RAS*|pho:RASGRP1@Golgi Apparatus
Identifiers
NAME:Ca2+:DAG:RAF1:RAS*:RASGRP1
References
su_mpk1_mpk1_re55( Survival
):
RasGTP and Sur-8 allow dephosphorylation of N-ter 14-3-3 binding site of Raf and thus its recruitment.
PMID:17496910
su_mpk1_mpk1_re58( Survival
):
Sef1 which is a putative transmembrane protein of the Golgi apparatus seems to be a scaffold protein that recruits ERK1/2 and MEK1/2 to its vicinity and probably allows their activation by Golgi-localised Ras proteins.
PMID:19565474
Modifications:
Participates in complexes:
In compartment: Golgi Apparatus
- Ca2+:DAG:RAF1|pho:RAS*|pho:RASGRP1@Golgi Apparatus
Participates in reactions:
As Reactant or Product:- RAF1@Cytoplasm
+ Ca2+:DAG:RAS*|pho:RASGRP1@Golgi Apparatus
→
Ca2+:DAG:RAF1|pho:RAS*|pho:RASGRP1@Golgi Apparatus
As Catalyser:- ERK*:MEK*:SEF*@Golgi Apparatus
→
ERK*|pho|pho:MEK*|pho|pho:SEF*@Cytoplasm