Complex BRCA1:E2F1:RB1
Complex composition:
- RB1
- E2F1
- BRCA1
BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho:E2F1:RB1@Nucleus
Identifiers
NAME:BRCA1:E2F1:RB1
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair
/ G1_S_CHECKPOINT
References
ce_re115( Cell Cycle DNA Repair
):
PMID:16581787,
For inhibition of S-checkpoint by ATM:
PMID:15175241
Inhibition of Sphase by MRE complex:
PMID:17713585
By CycE*/CDK2: G1/S transition
By CycD*/CDK2/CIp/KIP: checkpoint G1/S
Modifications:
Participates in complexes:
In compartment: Nucleus
- BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho:E2F1:RB1@Nucleus
Participates in reactions:
As Reactant or Product:- E2F1:RB1@Nucleus
+ BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho|active@Nucleus
→
BRCA1|S988_pho|S1387_pho|S1423_pho|S1497_pho|S1524_pho:E2F1:RB1@Nucleus
As Catalyser:- G1 phase@Nucleus
→
S phase@Nucleus