Complex PGE2:PTGER2 map
Complex composition:

  1. PTGER2 map
  2. PGE2 map

PGE2:​PTGER2@INNATE_IMMUNE_CELL_Membrane

Identifiers
NAME:PGE2:PTGER2

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / RECRUITMENT_OF_IMMUNE_CELLS  map

References
 MDSC  map
CASCADE:PGE2
PMID:22025564
PGE2 induces expression of CXCR4 in MDSC
Inhibition of COX2 or the PGE2 receptors EP2/EP4 in MDSCs suppressed expression of CXCR4 and MDSC responsiveness to CXCL12 or ovarian cancer ascites.

PGE2:​PTGER2@Cytosol

Identifiers
NAME:PGE2:PTGER2

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / INFLAMMATORY_SIGNALING_PATHWAYS  map

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. PGE2:​PTGER2@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. PGE2:​PTGER2@INNATE_IMMUNE_CELL_Membrane map
Participates in reactions:
As Reactant or Product:
  1. PGE2@default map + PTGER2@Cytosol map → map PGE2:​PTGER2@Cytosol map
  2. PGE2@default map + PTGER2@INNATE_IMMUNE_CELL_Membrane map → map PGE2:​PTGER2@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. gIL6@Cytosol map → map rIL6@Cytosol map
  2. gMIR149@Cytosol map → map arMIR149@Cytosol map
  3. Adenylyl_cyclase*@INNATE_IMMUNE_CELL_Cytosol map → map Adenylyl_cyclase*@INNATE_IMMUNE_CELL_Cytosol map
  4. gCXCR4@INNATE_IMMUNE_CELL_Cytosol map → map rCXCR4@INNATE_IMMUNE_CELL_Cytosol map