Reaction negative_influence su_wnc1_s_wnc1_re154 map

PTEN|​pho|​pho|​pho|​pho:​_beta_-Arrestin*@Cytoplasm map → Cell migration@Nucleus map

No reaction regulators

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

References
PTEN contains a C2-domain which inhibits cell migration. This inhibition works only when T383 is not phosphorylated
PMID:14976311
However, beta-arrestin can also bind PTEN in this C2-region thereby dis-inhibiting migration.
PMID:21642958