Protein UBE2T map

Identifiers
ubiquitin-conjugating enzyme E2T (putative)
HUGO:UBE2T, HGNC:25009, ENTREZ:29089, UNIPROT:Q9NPD8

Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
 Cell Cycle DNA Repair  map  / FANCONI  map
 Cell Cycle DNA Repair  map  / NER  map

References
PMID:19686080, PMID:19622404, PMID:18931676
Link between Fanconi and NER
PMID:22615860

UBE2T|​k91_ubi@Nucleus

References
ce_re213( Cell Cycle DNA Repair  map ):
PMID:19264559
FANCL induces UBE2T auto-ubiquitination on Lys91 by this inactivating UBE2T. This is a negative loop:
PMID:16916645

UBE2T@Nucleus

References
ce_re14( Cell Cycle DNA Repair  map ):
Link between Fanconi and NER
PMID:22615860
ce_re158( Cell Cycle DNA Repair  map ):
S phase checkpoint controls and induces FANCD2 monoubiquitusation to start Fanconi and HR
PMID:12239151
ce_re213( Cell Cycle DNA Repair  map ):
PMID:19264559
FANCL induces UBE2T auto-ubiquitination on Lys91 by this inactivating UBE2T. This is a negative loop:
PMID:16916645
ce_re252( Cell Cycle DNA Repair  map ):
Requirement for functional DNA polymerase eta in genome-wide repair by NER of UV-induced DNA damage during S phase:
PMID:20457011

Modifications:
In compartment: Nucleus
  1. UBE2T@Nucleus map
  2. UBE2T|​k91_ubi@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. UBE2T@Nucleus map → map UBE2T|​k91_ubi@Nucleus map
    2. UBE2T|​k91_ubi@Nucleus map → map degraded
    As Catalyser:
    1. gTC-NER_DNA_st2*@Nucleus map → map gTC-NER_GG-NER_DNA_st3*@Nucleus map
    2. FANCD2|​pho@Nucleus map → map FANCD2|​K561_ubi|​pho@Nucleus map
    3. FANCI|​pho@Nucleus map → map FANCI|​K523_ubi|​pho@Nucleus map
    4. UBE2T@Nucleus map → map UBE2T|​k91_ubi@Nucleus map
    5. gGG-NER_DNA_st1*@Nucleus map → map gGG-NER_DNA_st2*@Nucleus map