Protein KEAP1 map

Identifiers
kelch-like ECH-associated protein 1
HUGO:KEAP1 HGNC:23177 ENTREZ:9817 UNIPROT:Q14145

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / ANTIOXIDANT_RESPONSE  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / ER_STRESS  map
 Regulated Cell Death  map  / FERROPTOSIS  map

References
PMID:23850759

Modifications:
In compartment: Cytosol
  1. KEAP1@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. KEAP1:​NFE2L2@Cytosol map
  2. KEAP1:​NFE2L2@Cytosol map
  3. CUL3:​KEAP1:​RBX1@Cytosol map
In compartment: Ubiquitinated cargos
  1. KEAP1:​SQSTM1|​pho|​pho|​ubi@Ubiquitinated cargos map
Participates in reactions:
As Reactant or Product:
  1. KEAP1@Cytosol map + NFE2L2@Cytosol map → map KEAP1:​NFE2L2@Cytosol map
  2. SQSTM1|​pho|​pho|​ubi@Ubiquitinated cargos map + KEAP1@Cytosol map → map KEAP1:​SQSTM1|​pho|​pho|​ubi@Ubiquitinated cargos map
  3. NFE2L2@Cytosol map + KEAP1@Cytosol map → map KEAP1:​NFE2L2@Cytosol map
  4. KEAP1:​SQSTM1|​pho|​pho|​ubi@Ubiquitinated cargos map → map degraded
As Catalyser:
  1. BCL2@Cytosol map → map BCL2|​ubi@Cytosol map
  2. IKK_beta_*@Cytosol map → map IKK_beta_*|​ubi@Cytosol map
  3. NFE2L2@Cytosol map → map NFE2L2|​ubi@Cytosol map