Reaction state_transition rc_re416
NFE2L2@Cytosol
→ NFE2L2|ubi@Cytosol
Reaction regulators:
- Catalysis
- CUL3:KEAP1:RBX1@Cytosol
- KEAP1:NFE2L2@Cytosol
- Inhibition
- p21CIP1*@Cytosol
- ROS@Cytosol
References
PMID:19560419
CDKN1A interacts directly with NFE2L2, thus competing with KEAP1 binding