Protein RUNX2 map

Identifiers
runt-related transcription factor 2
HUGO:RUNX2, HGNC:10427, ENTREZ:860, UNIPROT:Q13950 , GENECARDS:GC06P045295
HUGO:RUNX2 HGNC:10472 ENTREZ:860 UNIPROT:Q13950 GENECARDS:RUNX2 REACTOME:63858 KEGG:860 ATLASONC:RUNX2ID42183ch6p21 WIKI:RUNX2

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / PI3K_AKT_MTOR  map

References
PMID:18497317
Notch1, Hey1, and Hey2 physically interact with and repress the function of the transcription factor RUNX2.
PMID:20946121
PMID:20580290

RUNX2@Nucleus

References
em_emtc_emtc_re1371( EMT Senescence  map ):
PMID:18497317
Notch1, Hey1, and Hey2 physically interact with and repress the function of the transcription factor RUNX2.

Modifications:
In compartment: Nucleus
  1. RUNX2@Nucleus map
Participates in complexes:
In compartment: Nucleus
  1. HEY1_2*:​RUNX2@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. rRUNX2@Nucleus map → map RUNX2@Nucleus map
  2. HEY1_2*@Nucleus map + RUNX2@Nucleus map → map HEY1_2*:​RUNX2@Nucleus map
  3. RUNX2@Nucleus map + gpromoter_region@Nucleus map → map su_akt1_s_akt2_s446
  4. FOXO1@Nucleus map + RUNX2@Nucleus map → map su_akt1_s_akt2_s432
As Catalyser: