Identifiers
NAME:HEY1_2*:RUNX2
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
References
PMID:18497317
Notch1, Hey1, and Hey2 physically interact with and repress the function of the transcription factor RUNX2.
PMID:16025100
Heys transcriptional repressors, which are activated by Notch1 signalling, physically interacted with Runx2 and repressed Runx2 transcriptional activity, independent of histone deacetylase activity.