Complex HEY1_2*:RUNX2 map
Complex composition:

  1. HEY1_2* map
  2. RUNX2 map


HEY1_2*:​RUNX2@Nucleus

Identifiers
NAME:HEY1_2*:RUNX2

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map

References
PMID:18497317
Notch1, Hey1, and Hey2 physically interact with and repress the function of the transcription factor RUNX2.
PMID:16025100
Heys transcriptional repressors, which are activated by Notch1 signalling, physically interacted with Runx2 and repressed Runx2 transcriptional activity, independent of histone deacetylase activity.


Modifications:
Participates in complexes:
In compartment: Nucleus
  1. HEY1_2*:​RUNX2@Nucleus map
Participates in reactions:
As Reactant or Product:
  1. HEY1_2*@Nucleus map + RUNX2@Nucleus map map HEY1_2*:​RUNX2@Nucleus map
As Catalyser: