Protein G_alpha_* map

Identifiers
guanine nucleotide binding protein (G protein) alpha 11 (Gq class)
HUGO:GNA11 HGNC:4379 ENTREZ:2767 UNIPROT:P29992
guanine nucleotide binding protein (G protein) alpha 12
HUGO:GNA12 HGNC:4380 ENTREZ:2768 UNIPROT:Q03113
guanine nucleotide binding protein (G protein) alpha 13
HUGO:GNA13 HGNC:4381 ENTREZ:10672 UNIPROT:Q14344
guanine nucleotide binding protein (G protein) alpha 14
HUGO:GNA14 HGNC:4382 ENTREZ:9630 UNIPROT:O95837
guanine nucleotide binding protein (G protein) alpha 15 (Gq class)
HUGO:GNA15 HGNC:4383 ENTREZ:2769 UNIPROT:P30679
guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 1
HUGO:GNAI1 HGNC:4384 ENTREZ:2770 UNIPROT:P63096
guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 2
HUGO:GNAI2 HGNC:4385 ENTREZ:2771 UNIPROT:P04899
guanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 3
HUGO:GNAI3 HGNC:4387 ENTREZ:2773 UNIPROT:P08754
guanine nucleotide binding protein (G protein) alpha activating activity polypeptide olfactory type
HUGO:GNAL HGNC:4388 ENTREZ:2774 UNIPROT:P38405
guanine nucleotide binding protein (G protein) alpha activating activity polypeptide O
HUGO:GNAO1 HGNC:4389 ENTREZ:2775 UNIPROT:P09471
guanine nucleotide binding protein (G protein) q polypeptide
HUGO:GNAQ HGNC:4390 ENTREZ:2776 UNIPROT:P50148
HUGO:GNA11 HGNC:4379 ENTREZ:2767 UNIPROT:P29992 GENECARDS:GNA11 REACTOME:55354 KEGG:2767 ATLASONC:GNA11ID43272ch19p13 WIKI:GNA11
HUGO:GNA12 HGNC:4380 ENTREZ:2768 UNIPROT:Q03113 GENECARDS:GNA12 REACTOME:55356 KEGG:2768 ATLASONC:GC_GNA12 WIKI:GNA12
HUGO:GNA13 HGNC:4381 ENTREZ:10672 UNIPROT:Q14344 GENECARDS:GNA13 REACTOME:55358 KEGG:10672 ATLASONC:GC_GNA13 WIKI:GNA13
HUGO:GNA14 HGNC:4382 ENTREZ:9630 UNIPROT:O95837 GENECARDS:GNA14 REACTOME:55360 ATLASONC:GC_GNA14 WIKI:GNA14
guanine nucleotide binding protein (G protein) alpha 15 5Gq class)
HUGO:GNA15 HGNC:4383 ENTREZ:2769 UNIPROT:P30679 GENECARDS:GNA15 REACTOME:55362 KEGG:2769 ATLASONC:GC_GNA15 WIKI:GNA15

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:21640127

Modifications:
Participates in complexes:
In compartment: Cytoplasm
  1. GDP:​G_alpha_*@Cytoplasm map
  2. GTP:​G_alpha_*@Cytoplasm map
  3. FZD*:​GDP:​G_alpha_*:​G_beta_*:​G_gamma_*@Cytoplasm map
  4. FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​WNT*@Cytoplasm map
  5. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*:​p120*@Cytoplasm map
  6. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map
  7. CK1_epsilon_*:​CTHRC1:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map
In compartment: Cytosol
  1. G_alpha_*:​PLC_beta_*@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. em_emtc_emtc_s4452 + PLC_beta_*@Cytosol map → map G_alpha_*:​PLC_beta_*@Cytosol map
  2. LGR5:​RSPO1-4*@Cytoplasm map + CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*:​p120*@Cytoplasm map → map CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map
  3. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map → map WNT canonical pathway@Cytoplasm map
  4. WNT*@default map + FZD*:​GDP:​G_alpha_*:​G_beta_*:​G_gamma_*@Cytoplasm map + GTP@Cytoplasm map → map FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​WNT*@Cytoplasm map + GDP@Cytoplasm map
  5. FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​WNT*@Cytoplasm map → map G_beta_*:​G_gamma_*@Cytoplasm map + GTP:​G_alpha_*@Cytoplasm map
  6. GTP:​G_alpha_*@Cytoplasm map → map GDP:​G_alpha_*@Cytoplasm map + Pi@Cytoplasm map
  7. GTP:​G_alpha_*@Cytoplasm map → map GTP:​G_alpha__sub_13q_endsub_*:​_beta_-Arrestin*@Cytoplasm map
  8. ROR2@Cytoplasm map + FZD*:​GDP:​G_alpha_*:​G_beta_*:​G_gamma_*@Cytoplasm map + WNT*@default map + GTP@Cytoplasm map + CK1_epsilon_*@Cytoplasm map + CTHRC1@Cytoplasm map + SYN4*@Cytoplasm map + PAR6*:​PRICKLE1|​pho:​RACK1*:​VANGL*@Cytoplasm map + PRR*@Cytoplasm map → map CK1_epsilon_*:​CTHRC1:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map + GDP@Cytoplasm map
  9. CK1_epsilon_*:​CTHRC1:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map → map GTP:​G_alpha_*@Cytoplasm map + CK1_epsilon_*:​CTHRC1:​FZD*:​PAR6*:​PRICKLE1|​pho:​PRR*:​RACK1*:​ROR2:​SYN4*:​VANGL*:​WNT*@Cytoplasm map + G_beta_*:​G_gamma_*@Cytoplasm map
As Catalyser:
  1. PI(4,5)P2@Mitochondria map → map I(1,4,5)P3@Mitochondria map + DAG@Cytosol map