Complex PDGF*:PDGFR* map
Complex composition:

  1. PDGFR* map
  2. PDGF* map

PDGF*:​PDGFR*@Cytosol

Identifiers
NAME:PDGF*:PDGFR*

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / GROWTH_FACTORS_SIGNALING_PATHWAYS  map

References
PMID:7682895; PMID:17397400
PDGF -receptor directly binds and activates PLC-gamma 1, RasGAP, P13K, and a 64 kd protein.
PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts downstream of PDGF signaling
ca_re278( Cancer Associated Fibroblasts  map ):
PMID:16713974
TLR signaling activates and IFNG inhibits PI3K pathway
PMID:11907067, PMID:15536084
SYK kinaze directly interacts with PI3K(p85) and activates perforin ??granule movement and polarization via PI3K /RAC1/PAK1/MEK??/ERK pathway
PMID:10426994??
Phosphorylated DAP10 directly interacts with regulatory subunit (p85) of PI3K and activates downstream pathway.

PDGF*:​PDGFR*@Membrane

Identifiers
NAME:PDGF*:PDGFR*

References
PMID:7682895 PMID:17397400

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. PDGF*:​PDGFR*@Cytosol map
In compartment: Membrane
  1. PDGF*:​PDGFR*@Membrane map
Participates in reactions:
As Reactant or Product:
  1. PDGF*@default map + PDGFR*@Cytosol map → map PDGF*:​PDGFR*@Cytosol map
  2. PDGF*@Membrane map + PDGFR*@Membrane map → map PDGF*:​PDGFR*@Membrane map
  3. PDGF*:​PDGFR*@Membrane map → map JAK/STAT_PATHWAY@Membrane map
  4. PDGF*:​PDGFR*@Membrane map → map PLCG_PATHWAYS@Membrane map
  5. PDGF*:​PDGFR*@Membrane map → map PI3K_PATHWAY@Membrane map
  6. PDGF*:​PDGFR*@Membrane map → map MAPK_PATHWAYS@Membrane map
As Catalyser:
  1. PI3KR(p85)*@Cytosol map → map PI3KR(p85)*@Cytosol map
  2. gSPP1@Cytosol map → map rSPP1@Cytosol map
  3. gFGF7@Cytosol map → map rFGF7@Cytosol map
  4. gFGF2@Cytosol map → map rFGF2@Cytosol map
  5. gSTC1@Cytosol map → map rSTC1@Cytosol map