Reaction state_transition ca_re278 map

PI3KR(p85)*@Cytosol map → PI3KR(p85)*@Cytosol map

Reaction regulators:
Catalysis
  1. PDGF*:​PDGFR*@Cytosol map
  2. GAB1|​pho@Cytosol map
  3. CCKBR:​GAST@Cytosol map


References
PMID:16713974
TLR signaling activates and IFNG inhibits PI3K pathway
PMID:11907067, PMID:15536084
SYK kinaze directly interacts with PI3K(p85) and activates perforin ??granule movement and polarization via PI3K /RAC1/PAK1/MEK??/ERK pathway
PMID:10426994??
Phosphorylated DAP10 directly interacts with regulatory subunit (p85) of PI3K and activates downstream pathway.