Protein Claudin2* map

Identifiers
claudin 2
HUGO:CLDN2, HGNC:2041, ENTREZ:9075, UNIPROT:P57739, GENECARDS:GC0XP106163

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / TIGHT_JUNCTIONS  map

Claudin2*@Cytosol

References
em_emtc_emtc_re519( EMT Senescence  map ):
PMID:22671595
Caveolin-1 is an endocytic scaffolding protein
It binds independently to claudin-2 and occludin (co-immunoprecipitation assays).
The finding that caveolin-1 interacts with claudin-2 and occludin, but notwith claudin-4 or ZO-1, suggests a potential mechanism for selective retrieval of tight junction components.

Modifications:
In compartment: Cytosol
  1. Claudin2*@Cytosol map
In compartment: Neighbouring Cell
  1. Claudin2*@Neighbouring Cell map
Participates in complexes:
In compartment: Cytosol
  1. Caveolin1*:​Claudin2*@Cytosol map
In compartment: Neighbouring Cell
  1. Claudin2*:​Claudin3*@Neighbouring Cell map
  2. Claudin2*:​Occludin*@Neighbouring Cell map
Participates in reactions:
As Reactant or Product:
  1. Claudin2*@Neighbouring Cell map + Claudin2*@Cytosol map → map em_s2506
  2. Claudin2*@Cytosol map + Claudin3*@Cytosol map → map Claudin2*:​Claudin3*@Neighbouring Cell map
  3. Occludin*@Cytosol map + Claudin2*@Cytosol map → map Claudin2*:​Occludin*@Neighbouring Cell map
  4. Caveolin1*@Cytosol map + Claudin2*@Cytosol map → map Caveolin1*:​Claudin2*@Cytosol map
  5. rClaudin2*@Nucleus map → map Claudin2*@Cytosol map
  6. Occludin_Claudin1_2_4_5_7_8_16*@Cytosol map → map Claudin2*@Cytosol map
  7. Claudin1_2_3_4*@Cytosol map → map Claudin2*@Cytosol map
  8. Claudin2*:​Occludin*@Neighbouring Cell map → map Tight junctions@Neighbouring Cell map
  9. Claudin2*:​Claudin3*@Neighbouring Cell map → map Tight junctions@Neighbouring Cell map
As Catalyser: