Identifiers
caveolin 1, caveolae protein, 22kDa
HUGO:CAV1, HGNC:1527, ENTREZ:857, UNIPROT:Q03135, GENECARDS:GC07P116164 ??

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence   / EMT_REGULATORS 
 EMT Senescence   / CELL_CELL_ADHESIONS 
 EMT Senescence   / TIGHT_JUNCTIONS 

References
PMID:22671595
Caveolin-1 is an endocytic scaffolding protein
It binds independently to claudin-2 and occludin (co-immunoprecipitation assays).
The finding that caveolin-1 interacts with claudin-2 and occludin, but notwith claudin-4 or ZO-1, suggests a potential mechanism for selective retrieval of tight junction components.

References
em_emtc_emtc_re518( EMT Senescence  ):
PMID:22671595
Caveolin-1 is an endocytic scaffolding protein
It binds independently to claudin-2 and occludin (co-immunoprecipitation assays).
The finding that caveolin-1 interacts with claudin-2 and occludin, but notwith claudin-4 or ZO-1, suggests a potential mechanism for selective retrieval of tight junction components.
em_emtc_emtc_re521( EMT Senescence  ):
PMID:15471980
PMID:17498653
The phosphorylation of caveolin-1 served to recruit C-terminal Src-like kinase (Csk) to the integrin/caveolin-1 complex.
This recruitment results in additional regulation of SFK activity and induction of myosin light chain (MLC) phosphorylation.
Key components of this pathway were recruited to caveolar microdomains and dependent on the presence of the caveolin-1 protein.
PMID:21051664
p190RhoGAP links integrins and caveolin-1 (and thus caveolae) to RhoA in a mechanotransduction cascade

1. Caveolin1*@Cytosol

1. Caveolin1*:​Claudin2*@Cytosol
2. Caveolin1*:​Occludin*@Cytosol

1. Occludin*@Cytosol + Caveolin1*@Cytosol → Caveolin1*:​Occludin*@Cytosol
2. Caveolin1*@Cytosol + Claudin2*@Cytosol → Caveolin1*:​Claudin2*@Cytosol
3. Caveolin1*@Cytosol + ITGB1@Cytosol → em_emtc_emtc_s2455