Identifiers
late endosomal/lysosomal adaptor MODULE:MAPK and MTOR activator 2
"roadblock domain containing 3" ROBLD3
HUGO:LAMTOR2 HGNC:29796 ENTREZ:28956 UNIPROT:Q9Y2Q5

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival   / MAPK 

References
P14 is an adaptor protein responsible for the recruitment of MP1 to late endosomes.
P14 is peripherally associated with the cytoplasmic face of late endosomes.
PMID:17178906 PMID:12479806

References
su_mpk1_mpk1_re17( Survival  ):
MP1 is localised on late endosomes by P14.
PMID:17178906

1. LAMTOR2@Late Endosomes

1. LAMTOR2:​MP1*@Late Endosomes
2. LAMTOR2:​MEK*:​MP1*@Late Endosomes
3. GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes
4. GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes
5. ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes

1. LAMTOR2@Late Endosomes + MP1*@Cytoplasm → LAMTOR2:​MP1*@Late Endosomes
2. MEK*@Cytoplasm + LAMTOR2:​MP1*@Late Endosomes → LAMTOR2:​MEK*:​MP1*@Late Endosomes
3. GRB2:​RAS*|​pho:​RTK*:​SOS*@Plasma Membrane + LAMTOR2:​MEK*:​MP1*@Late Endosomes → GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes
4. ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes → GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes + ERK*@Cytoplasm + RAF1@Cytoplasm
5. RAF1@Cytoplasm + GRB2:​LAMTOR2:​MEK*:​MP1*:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes → GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes
6. ERK*@Cytoplasm + GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes → ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes
7. ERK*|​pho|​pho:​GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes → GRB2:​LAMTOR2:​MEK*|​pho|​pho:​MP1*:​RAF1|​pho:​RAS*|​pho:​RTK*:​SOS*@Late Endosomes + ERK*|​pho|​pho@Cytoplasm