Protein PTPN13 map

Identifiers
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
HUGO:PTPN13 HGNC:9646 ENTREZ:5783 UNIPROT:Q12923

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / FAS_RESPONSE  map

References
PMID:12724420
FAP-1 (also known as PTPN13) association with Fas (Apo-1) inhibits Fas expression on the cell surface

PTPN13@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / FAS_RESPONSE  map

References
rc_re1671( Regulated Cell Death  map ):
FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface
PMID:12724420
rc_re1674( Regulated Cell Death  map ):
Apoptosis complex led by FAS ligation
PMID:12702723
PMID:9184224
PMID:23069999
PMID:16498403
caspase-8 formed triple complex with TRAF2 and FLASH. Taken together, these results suggest that endogenous caspase-8 mediates TNF-alpha-induced activation of NF-kappaB via FLASH

Modifications:
In compartment: Cytosol
  1. PTPN13@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. FAS:​FASLG@Cytosol map → map FAS@Vesicle map
      2. FASLG:​FAS|​pal@Cytosol map + Caspase8,10*:​FLASH*@Cytosol map + FAF1@Cytosol map + FADD@Cytosol map + DAXX@Cytosol map + RIPK1@Cytosol map → map Caspase8,10*|​ubi:​DAXX:​FADD:​FAF1:​FASLG:​FAS|​pal:​FLASH*:​RIPK1@Endosome map