Protein UNC5A map

Identifiers
unc-5 homolog A (C. elegans)
HUGO:UNC5A HGNC:12567 ENTREZ:90249 UNIPROT:Q6ZN44

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map

References
PMID:18582460
PMID:20173780
PMID:16829956
UNC5A promotes neuronal apoptosis

UNC5A@Cytosol

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / DEPENDANCE_RECEPTORS  map

References
rc_re1700( Regulated Cell Death  map ):
PMID:12376548
NRAGE may act to sequester and inactivate XIAP, leading to a potentiation of caspase-mediated cell death in a promyeloid leukemic cell line
PMID:11546791

Modifications:
In compartment: Cytosol
  1. UNC5A@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. NTN1:​UNC5A@Cytosol map
  2. NRAGE*:​UNC5A@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. NTN1:​UNC5A@Cytosol map → map NRAGE*:​UNC5A@Cytosol map + NTN1@Extracellular space map
  2. XIAP@Cytosol map + NRAGE*:​UNC5A@Cytosol map → map NRAGE*:​XIAP@Cytosol map + UNC5A@Cytosol map
As Catalyser:
  1. NRAGE*@Cytosol map + GEF*@Cytosol map → map GEF*:​NRAGE*@Cytosol map