Complex AXIN1:DVL1:FRAT1 map
Complex composition:

  1. AXIN1 map
  2. DVL1 map
  3. FRAT1 map

AXIN1:​DVL1:​FRAT1@Cytosol

Identifiers
NAME:AXIN1:DVL1:FRAT1

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / ADHERENS_JUNCTIONS  map

References
PMID:16288291
em_emtc_emtc_re466( EMT Senescence  map ):
PMID:10428961
PMID:8666229
Wnt transduces their signals through DVL1 to inhibit GSK3B, leading to the accumulation of cytosolic CTNNB1 and activation of TCF/LEF1 transcription factors.
DVL1 interacts with AXIN1 and with Frat1.
Binding of AXIN1 to DVL1 reduces formation of the destruction complex APC/AXIN1.

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. AXIN1:​DVL1:​FRAT1@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. AXIN1@Cytosol map + DVL1@Cytosol map + FRAT1@Cytosol map → map AXIN1:​DVL1:​FRAT1@Cytosol map
As Catalyser: