Protein PDGFRB map

Identifiers
HGNC:8804
platelet-derived growth factor receptor beta polypeptide
HUGO:PDGFRB HGNC:8804 ENTREZ:5159 UNIPROT:P09619

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map

References
PMID:17145802
RTKs exist as inactive monomers; after binding to their ligands they form dimers and their intracellular domains are activated.
PMID:17496910

Modifications:
In compartment: Cytosol
  1. PDGFRB@Cytosol map
  2. PDGFRB|​hm2|​active@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. PDGFRA:​PDGFRB@Cytosol map
  2. PDGFB:​PDGFRA:​PDGFRB@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. PDGFRA@Cytosol map + PDGFRB@Cytosol map → map PDGFRA:​PDGFRB@Cytosol map
  2. PDGFB@Extracellular Matrix map + PDGFRA:​PDGFRB@Cytosol map → map PDGFB:​PDGFRA:​PDGFRB@Cytosol map
  3. PDGFB:​PDGFRA:​PDGFRB@Cytosol map → map Lymphangiogenesis@Cytosol map
  4. PDGFR family*@Cytosol map → map PDGFRB@Cytosol map
  5. PDGF family*|​hm2:​PDGFR family*|​hm2@Cytosol map → map PDGFRB|​hm2|​active@Cytosol map
As Catalyser:
  1. STAT3@Cytosol map → map STAT3|​pho|​active@Cytosol map