Protein ARHGAP1 map

Identifiers
Rho GTPase activating protein 1
HUGO:ARHGAP1, HGNC:673, ENTREZ:392, GENECARDS:GC11M046698, UNIPROT:Q07960

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

References
PMID:9548756
RhoGAP1 (so-called ARHGAP1 or p50RhoGAP) is an RhoGTPase activiating protein.

ARHGAP1@Cytosol

References
em_emtc_emtc_re895( EMT Senescence  map ):
PMID:10551883
FGFR1 regulates activity of CDC42 by binding and phosphorylating thus inactivating BCL2.
Phosphorylated BCL2 binds to another CDC42_GAP, ARHGAP1 and neutralize the GAP activity of ARHGAP1 as well.

Modifications:
In compartment: Cytosol
  1. ARHGAP1@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. ARHGAP1:​BNIP2|​pho@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. RhoA_GAPs*@Cytosol map → map ARHGAP1@Cytosol map
  2. Rac1_GAPs*@Cytosol map → map ARHGAP1@Cytosol map
  3. CDC42_GAPs*@Cytosol map → map ARHGAP1@Cytosol map
  4. ARHGAP1@Cytosol map + BNIP2|​pho@Cytosol map → map ARHGAP1:​BNIP2|​pho@Cytosol map
As Catalyser: