Protein CDC42_GAPs* map

Identifiers
CDC42_GAPs*
Rho GTPase activating protein 1
HUGO:ARHGAP1, HGNC:673, ENTREZ:392, GENECARDS:GC11M046698, UNIPROT:Q07960
Rho GTPase activating protein 5
GFI2, "growth factor independent 2"
HUGO:ARHGAP5 HGNC:675 ENTREZ:394 UNIPROT:Q13017
Rho GTPase activating protein 17
HUGO:ARHGAP17 HGNC:18239 ENTREZ:55114 UNIPROT:Q68EM7
Rho GTPase activating protein 31
HUGO:ARHGAP31 HGNC:29216 ENTREZ:57514 UNIPROT:Q2M1Z3
Rho GTPase activating protein 32
HUGO:ARHGAP32, HGNC:17399, ENTREZ:9743, GENECARDS:GC11M128834, UNIPROT:A7KAX9
breakpoint cluster region
BCR1, D22S11
HUGO:BCR HGNC:1014 ENTREZ:613 UNIPROT:P11274
ralA binding protein 1
HUGO:RALBP1 HGNC:9841 ENTREZ:10928 UNIPROT:Q15311
active BCR-related
HUGO:ABR HGNC:81 ENTREZ:29 UNIPROT:Q12979
chimerin 2
HUGO:CHN2 HGNC:1944 ENTREZ:1124 UNIPROT:P52757
deleted in liver cancer 1
HUGO:DLC1 HGNC:2897 ENTREZ:10395 UNIPROT:Q96QB1

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

CDC42_GAPs*@Cytosol

References
em_emtc_emtc_re845( EMT Senescence  map ):
PMID:16371504
The endocytosis of trans-interacting E-cadherin was inhibited by Rac and Cdc42 small G proteins, which were activated by trans-interacting E-cadherin.
em_emtc_emtc_re874( EMT Senescence  map ):
PMID:8537347
PMID:10769036
ARHGAP5 as a GAP of CDC42
em_emtc_emtc_re875( EMT Senescence  map ):
PMID:12857875
ARHGAP32 as a GAP of CDC42
em_emtc_emtc_re878( EMT Senescence  map ):
PMID:7479768
PMID:8262969
ABR and BCR as a GAP of CDC42
em_emtc_emtc_re879( EMT Senescence  map ):
em_emtc_emtc_re880( EMT Senescence  map ):
PMID:16519628
ARHGAP31 as a GAP of CDC42
em_emtc_emtc_re881( EMT Senescence  map ):
PMID:16678097
ARHGAP17 as a GAP of CDC42
em_emtc_emtc_re882( EMT Senescence  map ):
PMID:14633674
DLC1as a GAP of CDC42
em_emtc_emtc_re883( EMT Senescence  map ):
PMID:10551883
FGFR1 regulates activity of CDC42 by binding and phosphorylating thus inactivating BCL2.
Phosphorylated BCL2 binds to another CDC42_GAP, ARHGAP1 and neutralize the GAP activity of ARHGAP1 as well.

Modifications:
In compartment: Cytosol
  1. CDC42_GAPs*@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CDC42_GAPs*@Cytosol map → map ARHGAP1@Cytosol map
    2. CDC42_GAPs*@Cytosol map → map ARHGAP5@Cytosol map
    3. CDC42_GAPs*@Cytosol map → map ARHGAP32|​Y_pho@Cytosol map
    4. CDC42_GAPs*@Cytosol map → map RALBP1@Cytosol map
    5. CDC42_GAPs*@Cytosol map → map CHN2@Cytosol map
    6. CDC42_GAPs*@Cytosol map → map ABR@Cytosol map
    7. CDC42_GAPs*@Cytosol map → map BCR@Cytosol map
    8. CDC42_GAPs*@Cytosol map → map ARHGAP31@Cytosol map
    9. CDC42_GAPs*@Cytosol map → map ARHGAP17@Cytosol map
    10. CDC42_GAPs*@Cytosol map → map DLC1@Cytosol map
    11. CDC42_GAPs*@Cytosol map → map BNIP2@Cytosol map
    As Catalyser:
    1. em_emtc_emtc_s3011 → map em_emtc_emtc_s3012