Phenotype Invasiveness map
Invasiveness@Cytosol

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map
 EMT Senescence  map  / ECM  map
 EMT Senescence  map  / TIGHT_JUNCTIONS  map
 EMT Senescence  map  / GAP_JUNCTIONS  map
 EMT Senescence  map  / ADHERENS_JUNCTIONS  map
 EMT Senescence  map  / DESMOSOMES  map

References
em_emtc_emtc_re1252( EMT Senescence  map ):
PMID:15252039
ID is so-called Inhibitor of differentiation/DNA binding proteins
ID proteins is frequently deregulated in advanced human malignancies.
ID proteins can participate in blocking differentiation, increasing proliferation, tissue invasiveness, and angiogenesis.
em_emtc_emtc_re1304( EMT Senescence  map ):
PMID:17332325
Of the 3 AKT isofomrs, AKT2 has been shown to promote cell motility, invasiveness and metastasis
em_re1513( EMT Senescence  map ):
PMID:19755709
Invadopodia are actin-rich membrane protrusions of cancer cells which facilitate pericellular proteolysis and invasive behavior.
em_re1507( EMT Senescence  map ):
PMID:26560033
EMT is not required for lung metastasis but contributes to chemoresistance

Modifications:
In compartment: Cytosol
  1. Invasiveness@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ID*@Nucleus map → map Invasiveness@Cytosol map
    2. AKT2@Cytosol map → map Invasiveness@Cytosol map
    3. EMT@Cytosol map → map Invasiveness@Cytosol map
    4. Invasiveness@Cytosol map → map Metastasis@Cytosol map
    5. Cell motility@Cytosol map → map Invasiveness@Cytosol map
    6. Invadopodia@Cytosol map → map Invasiveness@Cytosol map
    7. Migratory polarity@Nucleus map → map Invasiveness@Cytosol map
    As Catalyser: