Protein AKT2 map

Identifiers
v-akt murine thymoma viral oncogene homolog 2
HUGO:AKT2 HGNC:392 ENTREZ:208 UNIPROT:P31751

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / SENESCENCE  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / STARVATION_AUTOPHAGY  map
 Regulated Cell Death  map  / CASPASES  map
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map

References
PMID:17332325
Of the 3 AKT isofomrs, AKT2 has been shown to promote cell motility, invasiveness and metastasis
PMID:19825827
Decrease in the ratio of AKT1 versus AKT2 in cells induced the down-regulation of miR200 and promoted EMT and a stem cell-like phenotype.

AKT2@Cytosol

References
em_emtc_emtc_re1304( EMT Senescence  map ):
PMID:17332325
Of the 3 AKT isofomrs, AKT2 has been shown to promote cell motility, invasiveness and metastasis

Modifications:
In compartment: Cytosol
  1. AKT2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rAKT2@Nucleus map → map AKT2@Cytosol map
    2. AKT2@Cytosol map → map Invasiveness@Cytosol map
    3. AKT2@Cytosol map → map Metastasis@Cytosol map
    4. AKT2@Cytosol map → map Cell motility@Cytosol map
    5. AKT2@Cytosol map → map AKT*@Cytosol map
    As Catalyser: