Identifiers
Guanine nucleotide binding protein (G-protein) alpha inhibiting activity polypeptide 1
HUGO:GNAI1 HGNC:4384 ENTREZ:2770 UNIPROT:P63096 GENECARDS:GNAI1 REACTOME:55432 KEGG:2770 ATLASONC:GC_GNAI1 WIKI:GNAI1
Guanine nucleotide binding protein (G-protein) alpha inhibiting activity polypeptide 2
HUGO:GNAI2 HGNC:4385 ENTREZ:2771 UNIPROT:P04899 GENECARDS:GNAI2 REACTOME:55436 KEGG:2771 ATLASONC:GC_GNAI2 WIKI:GNAI2
Guanine nucleotide binding protein (G-protein) alpha inhibiting activity polypeptide 3
HUGO:GNAI3 HGNC:4387 ENTREZ:2773 UNIPROT:P08754 GENECARDS:GNAI3 REACTOME:55366 KEGG:2773 ATLASONC:GC_GNAI3 WIKI:GNAI3

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival   / HEDGEHOG 

References
PMID:17430994
Guanine nucleotide binding protein (G-protein)

1. G_alpha__sub_i_endsub_*:​Ligand@Cytosol
2. G_alpha__sub_i_endsub_*:​HH Ligand@Cytosol
3. G_alpha__sub_i_endsub_*:​G_beta__sub_i_endsub_*:​G_gamma__sub_i_endsub_*@Cytosol
4. G_alpha__sub_i_endsub_*:​G_beta__sub_i_endsub_*:​G_gamma__sub_i_endsub_*:​HH Ligand@Cytosol

1. su_shh1_s635 + G_alpha__sub_i_endsub_*:​G_beta__sub_i_endsub_*:​G_gamma__sub_i_endsub_*@Cytosol + GTP@Cytosol → G_alpha__sub_i_endsub_*:​G_beta__sub_i_endsub_*:​G_gamma__sub_i_endsub_*:​HH Ligand@Cytosol + GDP@Cytosol
2. G_alpha__sub_i_endsub_*:​G_beta__sub_i_endsub_*:​G_gamma__sub_i_endsub_*:​HH Ligand@Cytosol → su_shh1_s635 + SMO@Cytosol + su_shh1_s_shh1_s589 + G_beta__sub_i_endsub_*:​G_gamma__sub_i_endsub_*@Cytosol
3. su_shh1_s_shh3_s138 + su_shh1_s_shh3_s6 → G_alpha__sub_i_endsub_*:​HH Ligand@Cytosol
4. G_alpha__sub_i_endsub_*:​HH Ligand@Cytosol + GTP@Cytosol → G_alpha__sub_i_endsub_*:​Ligand@Cytosol + GDP@Cytosol
5. G_alpha__sub_i_endsub_*:​Ligand@Cytosol → PTCH*@Cytosol + su_shh1_s_shh3_s60 + G_beta_*:​G_gamma_*@Cytosol + SMO@Cytosol