Complex M20*:PPP1C*:PPP1R12A map
Complex composition:

  1. PPP1R12A map
  2. PPP1C* map
  3. M20* map

M20*:​PPP1C*:​PPP1R12A|​pho@Cytosol

Identifiers
NAME:M20*:PPP1C*:PPP1R12A

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MOTILITY  map

References
PMID:10953004
ROCK not only inhibits myosin phosphatase but also phosphorylates MLC directly in the center of cells (fibroblasts).

(M20*:​PPP1C*:​PPP1R12A)|​active@Cytosol

Identifiers
NAME:M20*:PPP1C*:PPP1R12A

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MOTILITY  map

References
PMID:15124925
Phosphorylation of myosin II plays an important role in many cell functions, including smooth muscle contraction. The level of myosin II phosphorylation is determined by activities of myosin light chain kinase and myosin phosphatase (MP). MP is composed of 3 subunits: a catalytic subunit of type 1 phosphatase, PPlc; a targeting subunit, termed myosin phosphatase target subunit, MYPT; and a smaller subunit, M20, of unknown function.
PMID:10953004
ROCK not only inhibits myosin phosphatase but also phosphorylates MLC directly in the center of cells (fibroblasts).

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. M20*:​PPP1C*:​PPP1R12A|​pho@Cytosol map
  2. (M20*:​PPP1C*:​PPP1R12A)|​active@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. (M20*:​PPP1C*:​PPP1R12A)|​active@Cytosol map → map M20*:​PPP1C*:​PPP1R12A|​pho@Cytosol map
As Catalyser:
  1. ELC_MYOSIN_II*:​MYH*|​hm2:​RLC_MYOSIN_II*|​pho@Cytosol map → map ELC_MYOSIN_II*:​MYH*|​hm2:​RLC_MYOSIN_II*@Cytosol map