Protein PPP1R12A map

Identifiers
protein phosphatase 1 regulatory subunit 12A
HUGO:PPP1R12A hgnc_id:HGNC:7618 HGNC:7618 ENTREZ:4659 UNIPROT:O14974

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MOTILITY  map

References
PMID:10953004
ROCK not only inhibits myosin phosphatase but also phosphorylates MLC directly in the center of cells (fibroblasts).

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. M20*:​PPP1C*:​PPP1R12A|​pho@Cytosol map
  2. (M20*:​PPP1C*:​PPP1R12A)|​active@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. (M20*:​PPP1C*:​PPP1R12A)|​active@Cytosol map → map M20*:​PPP1C*:​PPP1R12A|​pho@Cytosol map
As Catalyser:
  1. ELC_MYOSIN_II*:​MYH*|​hm2:​RLC_MYOSIN_II*|​pho@Cytosol map → map ELC_MYOSIN_II*:​MYH*|​hm2:​RLC_MYOSIN_II*@Cytosol map