Protein ERBB* map

Identifiers
erb-b2 receptor tyrosine kinase 2
HUGO:ERBB2 hgnc_id:HGNC:3430 HGNC:3430 ENTREZ:2064 UNIPROT:P04626
erb-b2 receptor tyrosine kinase 3
HUGO:ERBB3 hgnc_id:HGNC:3431 HGNC:3431 ENTREZ:2065 UNIPROT:P21860
erb-b2 receptor tyrosine kinase 4
HUGO:ERBB4 hgnc_id:HGNC:3432 HGNC:3432 ENTREZ:2066 UNIPROT:Q15303
HUGO:ERBB2 HUGO:ERBB3 HUGO:ERBB4

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / GROWTH_FACTORS_SIGNALING_PATHWAYS  map

References
PMID:10404636
EGFR interacts with most members of the c-erbB subfamily of RPTK.
PMID:20430953

Modifications:
In compartment: Cytosol
  1. ERBB*@Cytosol map
In compartment: Membrane
  1. ERBB*@Membrane map
Participates in complexes:
In compartment: Cytosol
  1. EGFR:​ERBB*@Cytosol map
In compartment: Membrane
  1. EGFR:​ERBB*@Membrane map
Participates in reactions:
As Reactant or Product:
  1. EGFR@Cytosol map + ERBB*@Cytosol map → map EGFR:​ERBB*@Cytosol map
  2. EGFR:​ERBB*@Cytosol map → map Fibroblast_proliferation@Cytosol map
  3. EGFR@Membrane map + ERBB*@Membrane map → map EGFR:​ERBB*@Membrane map
  4. EGFR:​ERBB*@Membrane map → map MAPK_PATHWAYS@Membrane map
  5. EGFR:​ERBB*@Membrane map → map PI3K_PATHWAY@Membrane map
  6. EGFR:​ERBB*@Membrane map → map PLCG_PATHWAYS@Membrane map
  7. EGFR:​ERBB*@Membrane map → map JAK/STAT_PATHWAY@Membrane map
As Catalyser:
  1. GRB2@Cytosol map → map GRB2@Cytosol map
  2. SHC1@Cytosol map → map SHC1|​pho@Cytosol map