→ DFFB@Cytosol + cleaved~DFFA*@Cytosol References
hierarchical:post-MOMP
reactionType:casp.cleavage
PMID:9108473
purification of DFFA:DFFB activity from Hela cells cytosol
in vitro, CASP3 mediated of DFFA necessary for nucleosomal DNA fragmentation
in U937 monocyte cells, in Hela cells, in SV589 human fibroblasts, upon staurosporin, DFFA cleaved into the same fragments as in vitro
PMID:9422506
purification and cloning of ICAD:CAD (mouse homologs) from mouse T-cell lymphoma cytosol
CASP3-mediated cleavage of ICAD releases CAD, leading to activation of its enzymatic activity and its nuclear localization