Complex TGFB1:TGFBR1:TGFBR2
Complex composition:
- TGFB1
- TGFBR1
- TGFBR2
TGFB1:TGFBR1:TGFBR2@Membrane
Identifiers
NAME:TGFB1:TGFBR1:TGFBR2
Maps_Modules
References
PMID:12809600
A TGFB ligand initiates signaling by binding to and bringing together type I and type II receptor serine/threonine kinases on the cell surface.
Modifications:
Participates in complexes:
In compartment: Membrane
- TGFB1:TGFBR1:TGFBR2@Membrane
Participates in reactions:
As Reactant or Product:- TGFB1@default
+ TGFBR1@Membrane
+ TGFBR2@Membrane
→
TGFB1:TGFBR1:TGFBR2@Membrane
As Catalyser:- SMAD3@Cytosol
→
SMAD3|pho@Cytosol
- SMAD2@Cytosol
→
SMAD2|pho@Cytosol