Complex PGE2:PTGER4 map
Complex composition:

  1. PGE2 map
  2. PTGER4 map

PGE2:​PTGER4@Membrane
MODULE:MDSC
PMID:22025564
PGE2 induces expression of CXCR4 in MDSC
Inhibition of COX2 or the PGE2 receptors EP2/EP4 in MDSCs suppressed expression of CXCR4 and MDSC responsiveness to CXCL12 or ovarian cancer ascites.
Modifications:
Participates in complexes:
In compartment: Membrane
  1. PGE2:​PTGER4@Membrane map
Participates in reactions:
As Reactant or Product:
  1. PGE2@default map + PTGER4@Membrane map → map PGE2:​PTGER4@Membrane map
As Catalyser:
  1. gARG1@Cytosol map → map rARG1@Cytosol map
  2. gCXCR4@Cytosol map → map rCXCR4@Cytosol map