Protein B7H4* map

Identifiers
HUGO:VTCN1

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / INHIBITING_CHECKPOINTS  map

References
PMID:12818165 PMID:24657487 PMID:28325750 PMID:12818166 PMID:29189263 PMID:28978159 PMID:12796776
 DENDRITIC_CELL  map
CASCADE:MACROPHAGE
PMID:12818165
Freshly isolated human T cells, B cells, monocytes, and DC do not express B7-H4 on cell surface in FACS analysis. In contrast, B7-H4 expression can be induced on T cells, B cells, monocytes, and DC after in vitro stimulation
B7H4 inhibits T-cell response.

Modifications:
In compartment: Cancer_cell
  1. B7H4*@Cancer_cell map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. B7H4*@Cancer_cell map → map Tcell_prolipheration@default map
    2. Ligands_of_Inhibiting_immune checkpoints@Cancer_cell map → map B7H4*@Cancer_cell map
    As Catalyser:
    1. CD28@T_cell map → map CD28|​pho|​active@cSMAC map
    2. BTLA@T_cell map + PTPN6@T_cell map + PTPN11@T_cell map → map BTLA:​PTPN11:​PTPN6@T_cell map
    3. rIFNG@T_cell map → map IFNG@T_cell map
    4. rIL10@T_cell map → map IL10@T_cell map
    5. rJUNB@T_cell map → map JUNB@T_cell map
    6. rIL4@T_cell map → map IL4@T_cell map