Protein MAP3K4 map

Identifiers
mitogen-activated protein kinase kinase kinase 4
HUGO:MAP3K4 hgnc_id:HGNC:6856 HGNC:6856 ENTREZ:4216 UNIPROT:Q9Y6R4
MEKK4
HUGO:MAP3K4 HGNC:6856 ENTREZ:4216 UNIPROT:Q9Y6R4

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / ER_STRESS  map
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / MAPK  map

References
PMID:24104473 PMID:16799472 PMID:11175814
PMID:23850759
MEKK4 is a MAP3K and can activate both JNK and P38 pathways. It may be an effector for stress pathways activated by genotoxins.
PMID:11274345

Modifications:
In compartment: T_cell
  1. MAP3K4@T_cell map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. MAP3K4@T_cell map → map MAP3K4@T_cell map
    As Catalyser:
    1. MAP2K4@T_cell map → map MAP2K4|​pho@T_cell map
    2. MAP2K3@T_cell map → map MAP2K3|​pho@T_cell map
    3. MAP2K6@T_cell map → map MAP2K6|​pho@T_cell map