Reaction known_transition_omitted em_emtc_emtc_re1136 map

gMIR183@Nucleus map arMIR183@Nucleus map

Reaction regulators:
Catalysis
  1. LEF1_TCF3_4*:​_beta_-Catenin*@Nucleus map
Inhibition
  1. ZEB1@Nucleus map


References
PMID:20706219
Feedback loop: ZEB1 inhibits expression of MIR203 and MIR183
PMID:19935649
ZEB1 directly controls transcription of the miR-203 and miR-183 and miR-200 family genes
PMID:24335145
??-Catenin/TCF/LEF-1 binds to the promoter of miR-183-96-182 cluster gene and thereby activates the transcription of the cluster.